BioGears

Mentors: Student: Rishi Das

<p>Up until the recent COVID-19 pandemic the greatest social/medical crisis in the United States has been the opioid epidemic, taking 128 lives a day per the CDC. Two of the high-level BioGears objectives are lowering the barrier to create medical training content and training the military. I believe that a clinically relevant comprehensive model of the naloxone reversal of fentanyl-induced respiratory depression could serve both as a training tool for emergency medical personnel as well as a predictive tool for the dose and frequency of nasally administered naloxone. Current guidelines for nasal naloxone usage are ambiguous and dependent on a wait-and-see approach instead of a high-fidelity data-driven predictive model, which risks under-usage of the life-saving drug due to basic human error.</p>

Mentors: Student: Shashank Jain

<p>There is a need for creation of such a website that is Python Extensible as the new models are needed to be added for plotting which are not supported in Java so there is a need to create such a website through which we can visualize the plots that are generated and Python as a software tool is required to visualize those outputs of models which are the plots of the required extension which are in the form of high resolution plots. In this process there is a need to remove the whole dependency of Java from the website and convert that to the Python based format for accessing them in the website and to support publication quality plots with high resolution.</p>